Long COVID with brain fog, pain and fatigue, much better on low-dose naltrexone
- Condition
- Long COVID
- At worst
- Moderate (mostly housebound)
- Ill before improving or writing
- 3 years
- Last post
- Sep 2024
In their words
- Condition: Long COVID
after 3 years of suffering with LC
In context ↗ - At worst: Moderate
i can sit in front of my computer and do my job without needing to nap every 45 minutes
In context ↗ - Now: Much better
i cant say im 100% back to normal, but im functional ... i still get PEM sometimes but its not as bad as it used to be
In context ↗ - Began after: COVID
after 3 years of suffering with LC
In context ↗
Summary
A Reddit user with long COVID for about three years cycled between partial recovery and relapse, trying many supplements and medications. In early 2024 low-dose naltrexone, started at 0.5 mg and increased by 0.5 mg every three months to 4.5 mg, gave 70% improvement within five days; by March they could work at the computer without napping every 45 minutes. By September they were functional; pain, brain fog and fatigue had subsided, though some PEM remained.
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What they tried
What they credit
Their words about each treatment
- LDN (low dose naltrexone) · Helped a lot
i cant say im 100% back to normal, but im functional, the pain, brain fog, and fatigue subsided, i still get PEM sometimes but its not as bad as it used to be
In context ↗
Their path
What they say at each step doesn’t fit the worst point or outcome above on the severity scale, so the steps are listed as they describe them. Dates are when they posted.
| When | What happened | After |
|---|---|---|
| 2021 | long COVID beganafter 3 years of suffering with LCIn context ↗ | |
| — | relapsed after a few months of semi-recoveryi would semi-recover for few months then i would relapse againIn context ↗ | |
| March 2024 | 70% better and able to work at the computer without constant napswithin 5 days im 70% betterIn context ↗ | Low-dose naltrexone |
| 2024-09-04 | functional; pain, brain fog and fatigue subsided, some PEM remainsim functional, the pain, brain fog, and fatigue subsided, i still get PEM sometimes but its not as bad as it used to beIn context ↗ | Low-dose naltrexone |
Adverse events
- Low-dose naltrexone“you'll get a flare up of symptoms when you first start using LDN but they should subside within a week or 2” In context ↗ Made symptoms worse
Symptoms mentioned
Their words about their symptoms
- Post-exertional malaise
i still get PEM sometimes but its not as bad as it used to be
In context ↗ - Brain fog
the pain, brain fog, and fatigue subsided
In context ↗ - Sleep problems
without needing to nap every 45 minutes
In context ↗
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