Moderate ME/CFS for years, now much better and back at work with low-dose naltrexone
- Condition
- ME/CFS
- At worst
- Moderate (mostly housebound)
- Ill before improving or writing
- Not stated
- Last post
- May 2026
In their words
- Condition: ME/CFS
Taking what I have has moved me from securely moderate to more mild level of ME/CFS.
In context ↗ - At worst: Moderate
I went from moderate to mild using LDN.
In context ↗ - Now: Much better
I'm back at work, studying for a PhD. I mostly work from home and my fiancé supports me a lot with day to day living. ... still managing variable ME but life is much bigger than it was.
Read from 18 of their posts and comments; links to the 11 this page draws on
Summary
Acorn 50420 had ME/CFS for years, describing herself in 2019 as heading from moderate to mild, then back at a securely moderate level. In November 2023 she began low-dose naltrexone and titrated very slowly to 0.25 ml morning and night, which she credits with moving her to a mild level. By 2026 she was back at work and studying for a PhD, mostly from home, though she still needed support and her ME remained variable.
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What they tried
What they credit
Also tried
Their words about each treatment
- Pacing · Helped
They taught me a lot about energy management, which isn't as easy as it sounds. I found it very helpful
In context ↗ - Meditation · Helped
Insight Timer has guided yoga nidra and free meditation music which I used to listen to a lot when I was very ill.
In context ↗ - shower seat · Helped
Having used the seat for a few months now, I find I can have showers more frequently and when i do have them i'm not now in bed all day.
In context ↗ - Ginger tea · Helped
I don't know if it actually does anything but it makes me feel like I'm doing something.
In context ↗ - Coenzyme Q10 (Mito q) · Helped
Coenzyme Q10 (Mito q)
In context ↗ - ALCAR · Helped
Hello. I also going find incredibly helpful.
In context ↗ - moving to a small town · Helped
I moved to a small town and have found a slower pace of life suits my health better.
In context ↗ - heart rate monitoring · Helped
I use heart rate monitoring. I find it really useful.
In context ↗ - LDN · Helped a lot
I went from moderate to mild using LDN. I'm now pursuing a PHD somewhat full time.
In context ↗
Approaches: Mould avoidance · Pacing
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, in the order they describe; they don’t give enough times to place each step. Hover or tap a point. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were | After |
|---|---|---|---|
| — | moderate ME/CFS baseline before gradual improvementI've been heading from moderate to mild over this past yearIn context ↗ | Moderate | |
| 2019-10-28 | gradual move from moderate towards mild over the past year | Mild | |
| 2020-05-04 | shower seat and occupational therapy advice stopped showers putting her in bed all dayI find I can have showers more frequently and when i do have them i'm not now in bed all dayIn context ↗ | Mild | |
| before November 2023 | back at a securely moderate level of ME/CFSI went from moderate to mild using LDN.In context ↗ | Moderate | |
| 2025-10-14 | moved from moderate to a more mild levelTaking what I have has moved me from securely moderate to more mild level of ME/CFS.In context ↗ | Mild | Low-dose naltrexone |
| 2026-05-10 | back at work and studying for a PhD, life much bigger but still variable MEstill managing variable ME but life is much bigger than it wasIn context ↗ | Mild |
Adverse events
- Low-dose naltrexone“If I take too much I am incredibly unwell, so I titrate very, very slowly.” In context ↗ Made symptoms worse
Symptoms mentioned
Their words about their symptoms
- Anxiety & low mood
The grief used to subsume me (at the most inconvenient times).
In context ↗
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