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ME/CFS Mild → somewhat betterNeeds ongoing treatment

Exhaustion with ME/CFS, now somewhat better on NMN with TMG and CoQ10

Condition
ME/CFS
At worst
Mild (working or studying, with limits)
Ill before improving or writing
Not stated
Last post
Nov 2025
In their words
  • Condition: ME/CFSI seem to be avoiding PEM more than before In context ↗
  • At worst: MildIt's enabled me to work from home which is a big deal. In context ↗
  • Now: Somewhat betterThis routine has really improved my well-being. No fix, "it's" still always there but it's far worse without this routine, for me. In context ↗
Read from 3 of their posts and comments; links to the 2 this page draws on

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Summary

They have not said how long they have been ill or how it began. NMN with TMG gave a mild energy rise, and adding NADH and CoQ10 gave a more notable lift; NADH/CoQ10 now come first thing and NMN in the afternoon. After about two months this routine has improved their wellbeing and enabled them to work from home, though exhaustion is always there and it is no fix. They take no pharmaceuticals.

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Asking aboutPetrel 43441’s story

What they tried

Their words about each treatment
  • NADH · HelpedI started without the NADH and added it, it is more if an early morning boost/kick start In context ↗
  • CoQ10 ubiquinol · HelpedI'm planning to go up to 200mg coq10 at next purchase. In context ↗
  • NMN · HelpedEarly to mid afternoon 600mg of NMN with electrolytes and TMG. In context ↗
  • TMG powder · HelpedThe NADH + COQ10 + NMN + TMG have objectively made things better for me. In context ↗
  • electrolytes · Not saidI add electrolytes to that with decent glass of water. In context ↗
  • standard multi · Not saidPlus standard multi, fish oil and misc. In context ↗

Approaches: Supplements

Their path

They say too little about how ill they were at each step to draw it on the severity scale, so the steps are listed as they describe them. Dates are when they posted.

WhenWhat happenedWhere they wereAfter
—living with CFS and constant exhaustion before supplementsit's far worse without this routine, for me In context ↗Not stated
—mild energy rise for a few hours from NMN with TMGI started taking NMN with TMG powder in the mornings and found it gave me a mild, but notable, energy rise for atleast a few hours. In context ↗Not statedNAD+ boosters (NMN, nicotinamide riboside, NADH, ATP)
—added NADH and CoQ10 after about six weeks, more notable energy liftDid this for about 6 weeks and then got the NADH and CoQ10 ubic. ... found a more notable energy lift compared to the NMN In context ↗Not statedNAD+ boosters (NMN, nicotinamide riboside, NADH, ATP)
2025-11-28about two months on the full stack, able to work from home, exhaustion still thereit has made my life better and I seem to be avoiding PEM more than before In context ↗Mild

Symptoms mentioned

Their words about their symptoms
  • Post-exertional malaiseI seem to be avoiding PEM more than before In context ↗

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