Bedbound for four months with ME/CFS, now much better after gabapentin and procyclidine
- Condition
- ME/CFS
- At worst
- Severe (mostly bedbound)
- Ill before improving or writing
- 4 years
- Last post
- Jun 2026
In their words
- At worst: Severe
extreme fatigue i was bedbound not able to open my eyes or lift my head
In context ↗ - Now: Much better
Since then, I've improved significantly—around 70% so far—and I still feel like I'm continuing to improve.
In context ↗
Read from 18 of their posts and comments; links to the 8 this page draws on
Summary
A man became bedbound for four months with severe insomnia, brain fog, migraine and muscle weakness after metoclopramide was prescribed for gastritis in April 2022. B complex injections gave a week of improvement in August 2022, then he improved slowly over three years to moderate with severe flare-ups, though he later said he had been bedridden most of the time. In 2026 gabapentin, procyclidine and a herbal remedy brought about 70% improvement, still continuing.
Ask Miruvor AI
What they tried
What they credit
Also tried
Their words about each treatment
- metoclopramide (primpran) · Much worse
he prescribed PPI,antacids, metoclopramide named primpran, antibiotics....once i took the drugs I wasn't the same.
In context ↗ - PPI, antacids · Not said
he prescribed PPI,antacids, metoclopramide named primpran, antibiotics
In context ↗ - B vitamins (B complex injections, then oral supplements) · Helped
B vitamins double dose worked for me
In context ↗ - sleeping pills · Not said
Yes, it makes me fall asleep but I wake after 2 hours and can't sleep again
In context ↗ - medications for the stomach, intestines and IBS · No change
I've tried every medication for the stomach, intestines, and irritable bowel syndrome, but nothing has worked.
In context ↗ - different diets · No change
I’ve also tried different diets, but the pain is still there.
In context ↗ - heat · No change
I've tried everything—medications, diets, and even heat—but nothing works.
In context ↗ - cyproheptadine / first generation antihistamines · Helped
First generation antihistamincs are veryhelpful ... cyproheptadine makes me sleep a lot but sedated all day
In context ↗ - gabapentin · Helped a lot
Two months ago, I started taking gabapentin and procyclidine along with some herbal remedies.
In context ↗ - ziziphus spina christi leaves · Helped
ziziphus spina christi leaves ..alone did nothing but with the other 2 drugs worked for me
In context ↗
Approaches: Alternative therapies · Other drugs and medicines · Supplements
Their path
What they say at each step doesn’t fit the worst point or outcome above on the severity scale, so the steps are listed as they describe them. Dates are when they posted.
| When | What happened | After |
|---|---|---|
| April 2022 | adverse reaction to metoclopramide prescribed for gastritisonce i took the drugs I wasn't the same.I felt some dizziness, headache at firstIn context ↗ | |
| 2022 | 10 days without sleep, then bedbound for four monthsextreme fatigue i was bedbound not able to open my eyes or lift my headIn context ↗ | |
| August 2022 | a week of injections brought immediate improvement, then symptoms returned milderduring that week i felt immediate improvementIn context ↗ | Vitamin B complex |
| February 2025 | gradual improvement to moderate with severe flare-upshere I am after three years of suffering I am moderate with severe flare upsIn context ↗ | |
| June 2026 | about 70% improved on gabapentin, procyclidine and a herbal remedy, still improvingSince then, I've improved significantly—around 70% so far—and I still feel like I'm continuing to improve.In context ↗ |
Adverse events
- Cyproheptadine (Periactin)“cyproheptadine makes me sleep a lot but sedated all day” In context ↗ Side effects
- “Yes, it makes me fall asleep but I wake after 2 hours and can't sleep again ...” In context ↗ Insomnia from treatment
- “apathy , i lost emotions... couldn't even cry” In context ↗ Mood or psychiatric effects
Symptoms mentioned
Their words about their symptoms
- Sleep problems
10 days with no sleep at all not even 10 seconds of sleep
In context ↗ - Brain fog
severe brain fog ( confusion , dizzy , not able to think
In context ↗ - Headaches & migraine
severe migraine all the time non stop whatever i did lasted for months
In context ↗ - Pain & fibromyalgia
generalized muscle pain , muscle twitching
In context ↗ - Muscle weakness
The medication caused me persistent headaches, severe heaviness and weakness
In context ↗ - Gut problems
I always have bloating and pain in my abdomen
In context ↗ - Light & noise sensitivity
sensitivity to light and sound , new allergies with sore throat
In context ↗ - Vision problems
partial hearing loss , severe blurred vision
In context ↗ - Anxiety & low mood
sudden severe depression (like u wanna ki''ll urself right now )
In context ↗ - Mast cell (MCAS) & allergies
new allergies with sore throat
In context ↗
Ask Miruvor AI
Similar stories
-
Very severe ME/CFS, now somewhat better and mostly bedbound after treating comorbidities
A COVID infection gave them mild ME/CFS; a second infection left them bedbound on and off and eventually very severe, with severe light and sound sensitivity. Low-dose naltrexone, gabapentin, clonidine, sodium cromolyn and other medications plus extreme rest…
-
Not enough detail to draw a path
Housebound with ME/CFS after mono, now much better after Lyme and babesia treatment
They were diagnosed with then-CFS after mono in 2003 aged 22, housebound two years, then relapsed in 2012 and were housebound four more years until treatment for Lyme and babesia brought remission. COVID in 2021 and 2024 each triggered long COVID;…
-
Long COVID with frontal-lobe damage, relapsed after reinfection; pacing, cannabis helped
After a COVID infection in 2020 the user developed long COVID, with frontal-lobe damage, spinal arthritis, recurring pericarditis and severe gluten issues. A second infection brought a relapse and an ischemic stroke. Duloxetine, gabapentin, antihistamines,…
-
Long COVID with suicidal ideation; LDN and lithium helped, then reinfection set them back
Caught COVID in January 2020, was long-hauling for almost three years with suicidal ideation, and improved somewhat on low-dose naltrexone and low-dose lithium, though a second infection in May 2022 worsened symptoms and they remained at about 50% recovered.