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Long COVID Mild → no benefit

Long COVID pins and needles for 2.5 years, no improvement from gabapentin or B vitamins

Condition
Long COVID
At worst
Mild (working or studying, with limits)
Ill for
Not stated
Last post
Apr 2026
In their words
  • Condition: Long COVIDanxiety is a big part of my LC In context ↗
  • At worst: MildI used to be a working guitarist but I had to stop. Between the tingling (left hand), anxiety, and fatigue, it just became too hard. In context ↗
  • Now: No benefitI'm just waiting for someone to figure out how to banish the COVID remnants from my brain and body. That's my main hope at this point. In context ↗
  • Began after: COVIDI tested positive in Oct/Nov '22... within a couple hours I started experiencing tingling (pins and needles) In context ↗
Read from 16 of their posts and comments; links to the 12 this page draws on

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Summary

After COVID in late 2022, this Reddit user developed pins and needles within hours; it settled in hands and feet, then the whole left side, unchanged for 2.5 years. Small fibre neuropathy was diagnosed after negative scans and an EMG; guitar work ended. Anti-anxiety meds (ashwagandha, later Cymbalta) helped most; NSAIDs and hot/cold eased tingling, while gabapentin, pregabalin and B vitamins did nothing. Cymbalta caused insomnia and/or dizziness.

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What they tried

Their words about each treatment
  • Ashwagandha (Nature's Bounty "Anxiety and Stress Relief") · Helped a lotThis was working very well for anxiety and helping me tremendously. In context ↗
  • Cymbalta (duloxetine) · HelpedIt also worked well (maybe slightly better) but I ended-up stopping it because of side-effects (insomnia and/or dizziness). In context ↗
  • Gabapentin · No changeI tried some drugs for nerve pain (Gabapentin, Pregablin (Lyrica), Alpha Lipoic acid supplements, and currently, Cymbalta), none have helped at all In context ↗
  • B12 supplements · No changeboth my PCP and neurologist checked my B12 (it was normal) and tried supplements -- my neurologist even tried an extra large dose -- nothing worked In context ↗
  • NSAIDs (Ibuprofen and Tylenol) · HelpedNSAIDS (Ibuprofen and Tylenol) seem to help minimize the intensity of the tingling In context ↗
  • hot/cold therapy · HelpedI use a heating pad for my hand all day, and sometimes move my hand onto a cold surface. In context ↗
  • guaifenesin (Mucinex) · HelpedI tried guaifenesin on a whim for dizziness (after much experience with sinus infections) and found that it helped. In context ↗
  • anti-histamines · HelpedFor me, the best ones have been: anti-anxiety (ashwaganda and Cymbalta), anti-histamines, NSAIDS, guaifenesin (for dizziness), relaxation (especially in a cool environment, perhaps using a fan), and hot/cold (for my nerve pain). In context ↗
  • B1 · No changerecently I tried a fairly high level of B1 In context ↗
  • inulin fiber prebiotic · HelpedAn inulin fiber prebiotic has helped me with this quite a bit. In context ↗

Their path

Very severeSevereModerateMildNear normalRecoveredonset3 mo6 mo9 mo

How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, with time counted from when the illness began. Hover or tap a point. Dates are when they posted. What the levels mean.

Show as a table
WhenWhat happenedWhere they were
Oct/Nov '22COVID infection; tingling began within hoursI tested positive in Oct/Nov '22... within a couple hours I started experiencing tingling (pins and needles) In context ↗Mild
Dec 2022tingling became persistent in both hands and feet, with cold feelingsone month later (Dec) it started persistently in my two hands and two feet, accompanied by cold feelings In context ↗Mild
Sep 2023tingling shifted to the whole left side of the bodynine months later (Sep, '23) one afternoon it suddenly and completely changed to the entire left side of my body from head to toe In context ↗Mild

Adverse events

Symptoms mentioned

Their words about their symptoms
  • Neuropathy & tinglingwithin a couple hours I started experiencing tingling (pins and needles) moving randomly around my body In context ↗
  • Anxiety & low moodanxiety is a big part of my LC In context ↗
  • Sleep problemsI fall asleep involuntarily, e.g. while watching TV In context ↗
  • POTS & dysautonomiaI have found that guaifenesin seems to help with dizziness In context ↗
  • Brain fogoften seems synchronized with my brain symptoms In context ↗
  • Gut problemsAn inulin fiber prebiotic has helped me with this quite a bit. In context ↗

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