Long COVID with blank mind and anhedonia, still severe after MAOI and TMS
- Condition
- Long COVID
- At worst
- Severe (mostly bedbound)
- Ill for
- Not stated
- Last post
- Jun 2025
In their words
- Condition: Long COVID
These symptoms were not directly LC initially, but a reaction to SRI given for LC.
In context ↗ - At worst: Severe
im too severe right now to make gains from these
In context ↗ - Now: No benefit
unfortunately still suffer blank mind and consummatory anhedonia
In context ↗ - Began after: COVID
These symptoms were not directly LC initially, but a reaction to SRI given for LC.
In context ↗
Read from 8 of their posts and comments; links to the 6 this page draws on
Summary
Vale 92525 had long COVID and developed blank mind and consummatory anhedonia so debilitating they said it took away hope; they traced the mental symptoms to a reaction to an SRI given for long COVID and crashed even harder on Wellbutrin. An MAOI (Parnate), TMS, mito supplements, oxaloacetate and NAD/MB IV gave only partial or temporary benefit, and they said they were currently too severe to make gains from these supplements.
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What they tried
Also tried
Their words about each treatment
- SRI · Worse
These symptoms were not directly LC initially, but a reaction to SRI given for LC.
In context ↗ - wellbutrin · Much worse
Crashed even harder on wellbutrin too
In context ↗ - Parnate · Helped
Parnate 10-20 mg, couldnt go higher due to blunting on it which felt SRI-like but backing down resolved that.
In context ↗ - coq10 · Not said
I take other mito supps like coq10, NMN, MB (used to help more but tolerance)
In context ↗ - oxaloacetate · Helped
recently oxaloacetate which helped some but im too severe right now to make gains from these
In context ↗ - TMS · Helped
Yea TMS helped general mood motivation, but it did not help consummatory anhedonia blank mind for me
In context ↗ - SS-31 · Helped
I also have taken SS-31 (mild temporary benefits)
In context ↗ - NAD MB IV · Helped
Ive done NAD MB IV also and this does help more but its temporary, not a lasting effect
In context ↗ - apollo neuro · No change
I have the apollo neuro and omnipemf but they dont help emotion, just calming
In context ↗
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, in the order they describe; they don’t give enough times to place each step. Hover or tap a point. 1 step says too little to place on the scale and is only in the table. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were |
|---|---|---|
| — | long COVIDThese symptoms were not directly LC initially, but a reaction to SRI given for LC.In context ↗ | Not stated |
| — | crashed even harder after Wellbutrin; SRI reaction brought on anhedonia and blank mindCrashed even harder on wellbutrin tooIn context ↗ | Severe |
| 2025-06-09 | still severe with anhedonia and blank mind; only partial or temporary gains from MAOI, TMS, mito supplements, oxaloacetate and NAD/MB IVim too severe right now to make gains from theseIn context ↗ | Severe |
Adverse events
- Tranylcypromine (Parnate)“Parnate 10-20 mg, couldnt go higher due to blunting on it which felt SRI-like but backing down resolved that.” In context ↗ Mood or psychiatric effects
- Antidepressants (unspecified), Bupropion (Wellbutrin), Tranylcypromine (Parnate)“These symptoms were not directly LC initially, but a reaction to SRI given for LC.” In context ↗ Mood or psychiatric effects
- Bupropion (Wellbutrin)“Crashed even harder on wellbutrin too” In context ↗ Made symptoms worse
Symptoms mentioned
Their words about their symptoms
- Brain fog
still suffer blank mind and consummatory anhedonia
In context ↗ - Anxiety & low mood
my anxiety is secondary to anhedonia which is the problem
In context ↗