Long COVID
Mild → somewhat better
Long COVID with post-exertional malaise, somewhat better with Bio-NAD+ and NR
- Condition
- Long COVID
- At worst
- Mild (working or studying, with limits)
- Ill before improving or writing
- Not stated
- Last post
- Mar 2026
In their words
- Condition: Long COVID
I'm relatively new to this and trying to stop the slide.
In context ↗ - At worst: Mild
I've got milking goats and they are not helping. Scared I'm going to have to sell them on.
In context ↗ - Now: Somewhat better
I'm enjoying having a less fuzzy brain and a bit more energy ... Struggling with the MCAS side of things really.
Read from 10 of their posts and comments; links to the 8 this page draws on
Summary
Relatively new to long COVID, Plover 43849 had post-exertional malaise that progressed to aching legs, then night flushing and broken sleep attributed to MCAS. Micropacing with a heart-rate monitor to stay below her lower lactate threshold is hard; Pharma Nord Bio-NAD+ at 250 mg raised energy and HRV, and 300 mg NR gave a similar boost. A swimming pool visit triggered a crash, the spa pool seemed to worsen MCAS symptoms, and flushing persisted.
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What they tried
Also tried
q10· HelpedPharma Nord Bio-NAD+ and NR· Helpedyoga nidra, humming and breathing exercises· HelpedNAC· Helpedlow histamine diet· HelpedDAO· HelpedH1 blockers· HelpedH2 blockers· Helped5htp· No changemicropacing with a heart rate monitor· No changeamitriptyline· WorseVisible and HRV4training apps· Not saidquercitin· Not saidbutterbur extract· Not said
Their words about each treatment
- 5htp · No change
I tried 5htp early on but noticed no difference
In context ↗ - amitriptyline · Worse
my gp wanted me to try amitriptyline, which was horrible
In context ↗ - micropacing with a heart rate monitor · No change
since my initial attempts at pacing were not working
In context ↗ - Visible and HRV4training apps · Not said
I measure HRV using 2 different apps, Visible and HRV4training
In context ↗ - q10 · Helped
I think I had problems with the sunflower oil/ gelatine capsule q10 but was ok with vegan capsules ... it does seem to help with my energy.
In context ↗ - Pharma Nord Bio-NAD+ and NR · Helped
I'm trying Pharma Nord Bio-NAD+ (nicotinamide/ nicotinic acid) at half the recommended dose (250mg) and felt an improvement in energy
In context ↗ - yoga nidra, humming and breathing exercises · Helped
Yoga nidra each day helps. Humming is good
In context ↗ - quercitin · Not said
have stopped the quercitin I was taking, since that might cause liver issues
In context ↗ - NAC · Helped
The nicatinamide and also NAC have significantly reduced my brain fog
In context ↗ - low histamine diet · Helped
The low histamine diet approach helps
In context ↗ - DAO · Helped
as does DAO, and H1/H2 blockers
In context ↗ - butterbur extract · Not said
I'm just trying butterbur extract, which is meant to be a leukotriene inhibitor.
In context ↗
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, in the order they describe; they don’t give enough times to place each step. Hover or tap a point. 2 steps say too little to place on the scale and are only in the table. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were | After |
|---|---|---|---|
| — | long COVID starting with fatigue-only PEMI used to just get this initiallyIn context ↗ | Not stated | |
| 2025-11-29 | symptoms progressed to aching legs; started heart-rate monitoring to paceI've started wearing a heart rate monitor all the time (an ancient Mio alpha) and trying to not go above my lower lactate thresholdIn context ↗ | Mild | |
| 2025-12-14 | more energy and raised HRV on half-dose Pharma Nord Bio-NAD+felt an improvement in energy which correlated with a significant increase in my HRVIn context ↗ | Mild | NAD+ boosters (NMN, nicotinamide riboside, NADH, ATP) |
| 2026-01-16 | crashed after swimming pool and spa; MCAS symptoms much worseclosely followed by a crash due to going to a swimming pool - the spa pool after seems to significantly worsen my MCAS symptoms!In context ↗ | Not stated | |
| 2026-01-16 | 300 mg NR gave a similar or better energy boost; brain fog reducedI've now tried 300mg NR and am getting a similar, if not better, boost in energy.In context ↗ | Mild | NAD+ boosters (NMN, nicotinamide riboside, NADH, ATP) |
| 2026-03-11 | still limited, sits for kitchen work and puzzles with a saddle stool; night flushing persistsWith all the sitting down I have to do it keeps my back in a more neutral position to,so I use it when I'm doing jigsaw puzzles too.In context ↗ | Mild |
Adverse events
- CoQ10 / ubiquinol“I think I had problems with the sunflower oil/ gelatine capsule q10 but was ok with vegan capsules.” In context ↗ Side effects
- Amitriptyline (Elavil)“I stopped since my gp wanted me to try amitriptyline, which was horrible.” In context ↗ Side effects
Symptoms mentioned
Their words about their symptoms
- Post-exertional malaise
closely followed by a crash due to going to a swimming pool
In context ↗ - Pain & fibromyalgia
now feel like I'm getting lactate build up in my legs as well so they ache
In context ↗ - Brain fog
The nicatinamide and also NAC have significantly reduced my brain fog.
In context ↗ - Mast cell (MCAS) & allergies
I'm still getting flushing at night messing up my sleep, that I think are histamine dumps.
In context ↗ - Sleep problems
I'm still getting flushing at night messing up my sleep
In context ↗