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Long COVID Moderate → recoveredIll 4 years before improving or writing

Severe long COVID for over a year, now recovered with antihistamines and a beta blocker

Condition
Long COVID
At worst
Moderate (mostly housebound)
Ill before improving or writing
4 years
Last post
Jun 2025
In their words
  • Condition: Long COVIDI developed long covid symptoms (SOB, palpitations, exhaustion, chest pain, GI issues). In context ↗
  • At worst: Moderate16 months in and I still can’t jog even 1/2 a mile. Can’t bike more than 20 minutes. In context ↗
  • Began after: a vaccinationMy symptoms only started after that second shot.
Read from 63 of their posts and comments; links to the 32 this page draws on

Request to remove this story

Summary

After mild COVID in April 2021 and a second Moderna dose in August 2021, he developed long COVID with severe breathlessness, chest pain, GI pain and fatigue. He was badly limited for over a year, with relapses after exercise and a flu. High-dose antihistamines, a beta blocker and nitroglycerin brought major improvement; colchicine helped but caused migraines. By June 2024 he reported almost 100% and was training for half Ironmans again; by June 2025 he reported 100%.

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What they tried

Their words about each treatment
  • return to triathlon training · WorseIf I try to train at all, I might be okay for a few days, but it catches up and I’m back to square one. In context ↗
  • omeprazole · No changeI was also prescribed omeprazole, which has not helped. In context ↗
  • albuterol inhaler · WorseI’ve tried albuterol, and that didn’t help at all. Made my chest burn even more. In context ↗
  • Primatene mist · HelpedI got over the counter primatine mist. Which is quite controversial.... But I have found it still helps on my runs In context ↗
  • rest / avoiding activity · Helpedwhen I refrain from all exercise and activity, all my symptoms reduce significantly In context ↗
  • keto diet · No changeJust started keto the other day. Eating less than 25g of carbs a day. Its only been a few days so I can't say it's done anything. In context ↗
  • multivitamin · No changeNo noticeable difference. Nothing has helped. In context ↗
  • B-12 · No changeI’ve tried all sorts of vitamins (currently taking a variety of B, and nattokinase). In context ↗
  • loratadine · No changeprescribed omeprazole, loratadine allergy meds ... No noticeable difference. In context ↗
  • baby aspirin · No changeI’ve tried daily aspirin and allergy pills. Nothing has been helping at all. In context ↗
  • quadramune · No changeTaking resveratrol + quadramune + Spermidine for a month now with no change. In context ↗
  • nattokinase · No changeJust started taking natokinase a week ago… I really hope my results are similar to yours. In context ↗
  • vitamin K2 · Not saidAlso taking an assortment of B vitamins, vitamin k2 and taurine. In context ↗
  • weekly 36 hour fasts · HelpedDid a months worth of weekly 36 hour fasts and my GI issues improved 90%. In context ↗
  • colchicine · HelpedI tried it for a few weeks and notice significant improvement in my LC symptoms. But I was getting raging migraines, nausea and fuzzy vision. In context ↗
  • nitroglycerin patch · HelpedI’m on a nitroglycerin patch and it’s helped all my other cardiac related symptoms. In context ↗
  • beta blocker · HelpedThe beta blocker helped keep my HR down while working out. In context ↗
  • fexofenadine · Helpedshe’s having me take 40 mg of famotidine 2x a day and 180 mg of fexofenadine 2x a day In context ↗
  • famotidine · Helpedshe’s having me take 40 mg of famotidine 2x a day ... it’s helped and I have no issues In context ↗
  • time · HelpedAnd I also think time has helped too. In context ↗
  • COVID vaccination as treatment · Not saidBoth 1st and 2nd shot resulted in extreme body soreness for 12 hours, hives, sore throat, and an odd pain sensation on my skin. In context ↗

Approaches: H1 antihistamines · H2 blockers · Beta-blockers

Their path

What they say at each step doesn’t fit the worst point or outcome above on the severity scale, so the steps are listed as they describe them. Dates are when they posted.

WhenWhat happened
August 2021Long COVID symptoms began after second Moderna doseI went from doing 15+ mile runs, 75+ mile bikes… to severe struggle walking up my stairs. In context ↗
December 2021Improved enough to run 10 miles without chest painI ran 10 miles the other day and didn't have a single sliver of chest pain. In context ↗
February 2022Symptoms returned as training picked upmy training has really picked up and my shortness of breath / chest pain has started coming back. In context ↗
March 2022Back to full daily activity and triathlon trainingI am back to 100% daily activity. Training for triathlons as usual with no serious issues. In context ↗
June 2022Symptoms worsened when training resumedAll the symptoms come back and get worse and worse as I continue training. In context ↗
August 2022Too limited to mow the yardNow I can't even mow my own yard. In context ↗
December 2022Colchicine reduced symptoms but caused migrainesI tried it for a few weeks and notice significant improvement in my LC symptoms. But I was getting raging migraines In context ↗
April 2023Able to run 4 miles on nitroglycerinIm now taking nitroglycerin… which is for people with heart blockages (I have none). Im finally able to ‘run’. I’ve worked up to 4 miles. In context ↗
July 2023Chest pain mostly gone after antihistamines and beta blockerI saw a lot of improvement through that trial. Im now off everything, my chest pain is pretty much gone but my breathing is still less than 50%. In context ↗
October 2023Running hard again with no breathing issues after runsI’m able to run and push myself hard. Did a 9 miler last week and a race pace 4 miler yesterday where my HR was steady at 175. In context ↗
December 2023Consistently running again without PEMRan 8 miles the other day with zero chest pain, no PEM either. Have been consistently running and pushing myself like I used to. In context ↗
June 2024Back to almost 100% and training for half IronmansIm back to almost 100%. Training for half Ironmans again with no issues. In context ↗
June 2025Reported 100% recovery

Adverse events

Symptoms mentioned

Their words about their symptoms
  • Post-exertional malaiseAny time I exert, my SOB is debilitating the rest of the day and days after. In context ↗
  • Brain fogI’ve had brain fog, blurry vision and migraines ever since. In context ↗
  • Headaches & migraineraging migraines, nausea and fuzzy vision In context ↗
  • Gut problemsGI pain is still here with a vengeance. In context ↗
  • BreathlessnessExtreme shortness of breath. Like a 24/7 asthma attack. In context ↗
  • Heart symptoms & palpitationssevere chest pain (feels like it’s right where my heart is) In context ↗
  • Anxiety & low moodnever been closer to suicide In context ↗

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