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Long COVID Severe → recoveredIll 2.5 years before improving or writing

Bedbound with long COVID, now recovered after Prozac

Condition
Long COVID
At worst
Severe (mostly bedbound)
Ill before improving or writing
2.5 years
Last post
May 2026
In their words
  • Condition: Long COVIDI've had LC now for 2 years. In context ↗
  • At worst: SevereI was bedbound and had to wear a eye mask because of severe mental fatigue. In context ↗
  • Now: RecoveredI've been pretty much 100% for the past 14 months In context ↗
  • Began after: COVIDI had covid May of 2022 and began having leg pains some time that August. In context ↗
Read from 37 of their posts and comments; links to the 21 this page draws on

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Summary

Horizon 15103 fell ill after COVID in May 2022 with leg pain, head pressure and POTS-like symptoms, then crashed in March 2023 and was briefly bedbound. They used nicotine patches, LDN and supplements and were near 100% by mid-2023, but late-2023 reinfection/exposure preceded a worse relapse, housebound with severe screen sensitivity through 2024 and later bedbound with severe mental fatigue. After starting Prozac in 2025 they reported remission and were about 100% for 14 months by May 2026.

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What they tried

Their words about each treatment
  • Klonopin · HelpedKlonopin was definitely a convenient thing to have at times. In context ↗
  • Nicotine patches · HelpedI started nicotine patches a week after my crash. Started recovering in a non-linear fashion until about June. In context ↗
  • LDN · Not saidI also ramped up my LDN and it's making it worse actually. About to go back down to 3mg. In context ↗
  • apolactoferrin · Not saidAlso using LDN, apolactoferrin, NAC In context ↗
  • NAC · Not saidapolactoferrin, NAC, daily electrolytes In context ↗
  • daily electrolytes · Not saidNAC, daily electrolytes, multivitamin In context ↗
  • multivitamin · Not saiddaily electrolytes, multivitamin, probiotics In context ↗
  • probiotics · Not saidmultivitamin, probiotics, Renue By Science AM Activator In context ↗
  • Renue By Science AM Activator · Not saidprobiotics, Renue By Science AM Activator and NA semax amidate nasal In context ↗
  • NA semax amidate nasal · Not saidRenue By Science AM Activator and NA semax amidate nasal In context ↗
  • Paxlovid · Not saidCaught covid again 1 year in and took paxlovid. Was negative in 3 days. In context ↗
  • Lexapro · WorseLexapro made my muscle fatigue worse. Got off of it quicky. In context ↗
  • iv migraine medication · WorseI had the same jump out of my skin reaction to a iv migraine medication I was given. In context ↗
  • low dose abilify · No changeNothing that I've noticed. Maybe a slight boost for the first 2 weeks, then nothing. In context ↗
  • aggressive rest · HelpedYeah, it's definitely better, but still screen sensitivity. Aggressively rested for 2 weeks straight. In context ↗
  • Truvada · No changeI tried Truvada. Didn't help. In context ↗
  • prozac · Helped a lotI started prozac and am now in remission.. Back to work and just went on a cruise where I was doing 15k steps a day. In context ↗

Approaches: SSRIs · Radical rest

Their path

Very severeSevereModerateMildNear normalRecoveredonset12 mo2 y3 y

How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, with time counted from when the illness began. Hover or tap a point. Dates are when they posted. What the levels mean.

Show as a table
WhenWhat happenedWhere they were
August–October 2022long COVID began with leg pains, then head pressure and POTS-like symptomsthe extreme head pressure started in September followed by POTS like symptoms which sent me to the ER twice in early October In context ↗Severe
February into March 2023gradual improvement to about 90% of normalFeb into March 90% to almost 100% In context ↗Near normal
late March 2023crashed after heavy gym workouts and a night of heavy drinkingI felt like I could barely move ... I was basically bedbound In context ↗Severe
April 2023back to about 90% after the March crashI'm back to 90% today and being more cautious. In context ↗Near normal
June 2023a month of feeling pretty much 100%I've gone a month feeling pretty much 100%. In context ↗Near normal
August–September 2023COVID reinfection; old symptoms returned a month latercaught COVID again at the end of August ... One month later I started having some old symptoms again. In context ↗Mild
December 2023back to 100% after the post-reinfection resurgenceI feel 100% now. In context ↗Recovered
January 2024symptoms ramped back up after December 2023 exposureMy LC symptoms started to ramp back up in January. In context ↗Moderate
August 2024worsening neurological symptoms and screen sensitivity; houseboundI basically have to keep my eyes closed most of the day to keep things from getting worse. In context ↗Severe
October 2024rolling crashes settled to moderateRolling crashes led to moderate i think. In context ↗Moderate
May 2025in remission, back at work and doing 15,000 steps a dayI started prozac and am now in remission.. Back to work and just went on a cruise where I was doing 15k steps a day. In context ↗Recovered
May 2026about 100% for the past 14 monthsI've been pretty much 100% for the past 14 months In context ↗Recovered

Adverse events

Symptoms mentioned

Their words about their symptoms
  • Post-exertional malaiseGot the pem/cfs type this time. In context ↗
  • Brain fogHad severe brain fog and could barely grip things at times. In context ↗
  • POTS & dysautonomiaPOTS like symptoms which sent me to the ER twice in early October In context ↗
  • Pain & fibromyalgiaI had covid May of 2022 and began having leg pains some time that August. In context ↗
  • Headaches & migrainethe extreme head pressure started in September In context ↗
  • Vision problemsmy vision was affected In context ↗
  • Muscle weaknessstill felt like my legs weighed a ton In context ↗
  • Heart symptoms & palpitationsI had some light heart palpitations, tightness in chest In context ↗
  • Flu-like symptomsgeneral malaise like I had caught something In context ↗
  • Anxiety & low moodI'm recovered, but definitely have some sort of PTSD from the whole fiasco. In context ↗

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