Long COVID breathlessness, no improvement after supplements and hyperbaric oxygen
- Condition
- Long COVID
- At worst
- Mild (working or studying, with limits)
- Ill for
- 4.5 years
- Last post
- Sep 2026
In their words
- Condition: Long COVID
caught omicron Dec ‘21, long hauling ever since
In context ↗ - At worst: Mild
I have worked straight through all of this ... at a greatly reduced productive capacity
In context ↗ - Now: No benefit
just my symptoms never resolved
In context ↗ - Began after: COVID
caught omicron Dec ‘21, long hauling ever since
In context ↗
Read from 69 of their posts and comments; links to the 42 this page draws on
- Oct 2022
- Oct 2022
- Sep 2026
- Feb 2022
- Feb 2022
- Jan 2023
- Mar 2022
- May 2022
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- May 2024
- Jul 2022
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- Dec 2023
- Jan 2024
- Sep 2026
- Jun 2022
- Nov 2023
Summary
A Texas veterinarian caught COVID in December 2021 and has had long COVID since, with breathlessness, chest pain, insomnia and post-exertional malaise. A third Moderna booster in mid-2022 caused a major setback she never fully recovered from. She kept working at reduced capacity while trying supplements, hyperbaric oxygen, low-dose naltrexone and fasting, with only small gains such as better sleep and higher resting oxygen.
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What they tried
Also tried
Their words about each treatment
- Sleepzyme (melatonin-based supplement) · No change
I’ve been taking a melatonin-based supplement (Sleepzyme) which has various herbal compounds, but it leaves me groggy and STILL not feeling well rested.
In context ↗ - Trazodone · Worse
A therapist years ago Rx’d Trazodone which left me with even worse “hangover” symptoms; it just wasn’t worth it to me!
In context ↗ - Wellbutrin · Worse
I had to give it up after about a week of low-grade GI misery and a strange incipient headache
In context ↗ - Lexapro · Worse
over past decades of struggles against chronic depression & anxiety, I’ve tried several but found side effects intolerable: Wellbutrin, Lexapro, Trazodone, Zoloft
In context ↗ - Acupuncture · Not said
I started acupuncture treatments three weeks ago - he shows me pretty colored bars on graphs which are changing; it also seems to have triggered some night sweats but hard to say if it is helping to any great extent at this point?
In context ↗ - Hot yoga / low-intensity yoga · Helped
Even then there’s a price to be paid with minor “crash” the day after, but it’s worth it as much for my mental health as the physical benefits.
In context ↗ - Famotidine · Worse
Famotidine doesn’t seem to help my brain fog - in fact it seems to exacerbate it.
In context ↗ - Sertraline · Helped
I’ve been taking low-dose sertraline these past couple of weeks which seems to be helping with my sleep
In context ↗ - Ibuprofen · Helped
So far it does seem to be responding to ibuprofen, thank goodness.
In context ↗ - Chinese herbs (Long Haul Tea) · No change
Yep I drank it for a good solid month - it certainly didn’t hurt anything except my taste buds, but I can’t really say it did me any good?
In context ↗ - B-complex · Helped
I have been on my “enhanced supplement protocol” which includes B-complex, black seed oil, quercetin, CoQ10, etc for several months & while it may be helpful, it hasn’t been phenomenally so.
In context ↗ - Black seed oil · Helped
as I empty out these bottles, the only ones I will replace is the nattokinase and blackseed oil
In context ↗ - Quercetin · Not said
Right now I’m taking only magnesium, blackseed oil, & quercetin, when I finish off the quercetin I’ll probably discontinue it as well.
In context ↗ - Colchicine · Not said
I started taking colchicine last week; too soon to tell if it is helping much (yet)?
In context ↗ - Moderna third booster · Much worse
I let my new doctor talk me into a third Moderna booster last week - it has caused a major setback with worsening shortness of breath/heart palpitations
In context ↗ - Low-dose naltrexone · Helped
this micro dose does seem to help my sleep quite a bit.
In context ↗ - Magnesium · Not said
Magnesium is primarily for sleep (ha ha)
In context ↗ - CBD · Helped
I have been taking some CBD which seems to help
In context ↗ - Melatonin · Not said
For sleep I am taking magnesium, CBD, low-dose melatonin
In context ↗ - Yoga nidra · Helped
Yoga nidra FTW! I listen to a short session every night - it helps me fall asleep.
In context ↗ - Yogic breathing exercises · Not said
I have been taking some CBD which seems to help and practicing yogic breathing exercises
In context ↗ - Herbal powders · Not said
several herbal powders recommended by an Eastern-medicine guru whom I follow
In context ↗ - Cetirizine · Worse
Most antihistamines knock me on my ass, cetirizine was no exception although it didn't hit me "quite" as hard as other antihistamines.
In context ↗ - Aspirin · Helped
I took nattokinase for months with no real improvement, so I’ve gone back to low-dose aspirin which does seem to help
In context ↗ - ImmunoShot (glutathione, vitamin C, zinc injection) · Worse
These vitamin infusions may work great for some folks, but my system did not appreciate at all!
In context ↗ - Tramadol · Not said
took a Tramadol when I got home
In context ↗ - Tylenol · Not said
I’ve taken my ibuprofen & Tylenol
In context ↗ - Probiotics · Not said
Some GI distress with bloat (4 lbs overnight, really??) for which I took some probiotics.
In context ↗ - Lithium orotate · Much worse
Lithium orotate even at micro dose levels (2.5 mg, 1/4 tablet) knocked me on my butt.
In context ↗ - Spike Protein supplement (natto & herbal compounds) · Worse
I have felt worse since starting a new “Spike Protein” supplement (it has natto & several other herbal compounds)
In context ↗ - Nattokinase · No change
I took nattokinase for months with no real improvement
In context ↗ - Cymbalta · Worse
Two months ago she talked me into trying Cymbalta - I took it for about two weeks and then I set it aside, the low-grade GI misery just wasn’t worth it.
In context ↗ - Cannabis gummy · Helped
for anxiety relief I will take a fractionated gummy on occasion - the problem is THC makes me very lazy!
In context ↗ - Thiamine · Not said
the plentiful rack o’ supplements (natto, BSO, thiamine, bibbity bobbity boo with Chinese herbs recommended by another long hauler which didn’t help much)
In context ↗ - Dandelion root capsules · Not said
Currently taking quercetin, CoQ10, BSO, & dandelion root capsules.
In context ↗ - Radical rest · Helped
I also cannot retire & have managed to “keep on keeping on” by radically resting, marshaling my limited energy reserves to struggle through each workday.
In context ↗ - Hyperbaric oxygen (HBOT) · Helped
main benefit I have noticed is gradual increase in my resting pO2, which has crept up from 93 to 97%.
In context ↗ - Intermittent fasting / OMAD · Helped
But I DO feel better overall if I stick to an OMAD routine
In context ↗ - Oral thyroid replacement · Not said
I have been thyroidectomized so 100% reliant on oral thyroid replacement
In context ↗ - Artificial tear solution · Not said
I use artificial tear solution, but sometimes I wake up in considerable discomfort
In context ↗
Their path
How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, with time counted from when the illness began. Hover or tap a point. The chart starts 3 months after onset: the story doesn’t say how ill they were before that. 1 step says too little to place on the scale and is only in the table. Dates are when they posted. What the levels mean.
Show as a table
| When | What happened | Where they were | After |
|---|---|---|---|
| December 2021 | COVID infection (omicron)caught omicron Dec ‘21, long hauling ever sinceIn context ↗ | Not stated | |
| March 2022 | slow improvement over first monthsI do seem to be slowly improving (a little over 3 mos out)In context ↗ | Mild | |
| May 2022 | relapse after overdoing it on Mother's Day weekendwhen I have a good day & try to do too much, invariably I will relapse and put myself back in the ditch. (such was the case after Mother’s Day weekend)In context ↗ | Mild | |
| June 2022 | crashed after third Moderna boosterI let my new doctor talk me into a third Moderna booster last week - it has caused a major setback with worsening shortness of breath/heart palpitationsIn context ↗ | Mild | |
| September 2022 | slow gains, managing low-intensity yogaI’m 9 mos in, the best I can manage these days are low-intensity yoga classes. Even then there’s a price to be paid with minor “crash” the day afterIn context ↗ | Mild | |
| October 2022 | severe relapse after judging an equestrian event on her feet all dayjudged an equestrian event Saturday which required me to be up early & stay on my feet most of the day, so now I am suffering a severe relapseIn context ↗ | Mild | |
| December 2023 | resting oxygen levels crept up with hyperbaric oxygenmy pO2 reads 97 which is the highest it’s been in months (used to hang around 92-3, but has crept up point by point since I started hyperbaric oxygen treatments these past 6 wksIn context ↗ | Mild | Hyperbaric oxygen (HBOT) |
| January 2024 | still limited going into year threeHeading into Year 3 & this may be as good as it gets?In context ↗ | Mild | |
| April 2025 | felt better overall on one meal a dayBut I DO feel better overall if I stick to an OMAD routineIn context ↗ | Mild | Intermittent fasting |
| September 2026 | still long hauling, intermittent fasting helpfulI have done intermittent fasting, which seems to be helpfulIn context ↗ | Mild | Intermittent fasting |
Adverse events
- “I’ve been taking a melatonin-based supplement (Sleepzyme) which has various herbal compounds, but it leaves me groggy and STILL not feeling well rested.” In context ↗ Side effects
- Trazodone (Desyrel)“A therapist years ago Rx’d Trazodone which left me with even worse “hangover” symptoms; it just wasn’t worth it to me!” In context ↗ Side effects
- Trazodone (Desyrel)“new MD is trying to be helpful but so far trazodone leaves me even more flatline depressed & I refuse to take an SSRI” In context ↗ Mood or psychiatric effects
- Acupuncture“it also seems to have triggered some night sweats but hard to say if it is helping to any great extent at this point?” In context ↗ Side effects
- COVID vaccination as treatment“it has caused a major setback with worsening shortness of breath/heart palpitations, muscular soreness, low-grade headache and just generally feeling like crap.” In context ↗ Made symptoms worse
- Famotidine (Pepcid)“Famotidine doesn’t seem to help my brain fog - in fact it seems to exacerbate it.” In context ↗ Made symptoms worse
- Sertraline (Zoloft)“the half-doses of sertraline I took as a sleep aid likewise left me feeling worse instead of better.” In context ↗ Side effects
- Chinese herbal medicine (TCM formulas)“It kinda hit my GI tract like a depth charge ... luckily only moderate cramping, bloat & gas.” In context ↗ Gut side effects
- Low-dose naltrexone“I took 1.5 mg twice last weekend, then I couldn’t understand why I was so zombified? I was extremely drowsy, seemed as if I could never “wake up” even with extra caffeine.” In context ↗ Side effects
- Bupropion (Wellbutrin)“it didn’t sit well with me - I had to give it up after about a week of low-grade GI misery and a strange incipient headache” In context ↗ Side effects
- Cetirizine (Zyrtec)“Most antihistamines knock me on my ass, cetirizine was no exception although it didn't hit me "quite" as hard as other antihistamines.” In context ↗ Side effects
- IV vitamins and Myers cocktail“this morning I am really stiff & sore, with a flare-up of generalized joint pain and lethargy, all I want to do is crawl back into bed even though I slept fairly decently.” In context ↗ Made symptoms worse
- Lithium orotate (low-dose)“Lithium orotate even at micro dose levels (2.5 mg, 1/4 tablet) knocked me on my butt.” In context ↗ Side effects
- Nattokinase“I have felt worse since starting a new “Spike Protein” supplement (it has natto & several other herbal compounds)” In context ↗ Made symptoms worse
- Duloxetine (Cymbalta)“I took it for about two weeks and then I set it aside, the low-grade GI misery just wasn’t worth it.” In context ↗ Gut side effects
- Cannabis (THC, marijuana)“the problem is THC makes me very lazy!” In context ↗ Side effects
Symptoms mentioned
Their words about their symptoms
- Sleep problems
the night passes for me in a series of naps, tossing & turning
In context ↗ - Post-exertional malaise
Mild to moderate PEM but anything is better then complete inactivity
In context ↗ - Breathlessness
Cardiac symptoms with shortness of breath predominate
In context ↗ - Heart symptoms & palpitations
My heart rate accelerates dramatically with even mild exertion
In context ↗ - Brain fog
I am suffering from worsened brain fog with tinnitus
In context ↗ - Pain & fibromyalgia
a strange assortment of musculoskeletal aches & pains
In context ↗ - Headaches & migraine
A new symptom has appeared - late night headaches
In context ↗ - Gut problems
bloating and GI misery
In context ↗ - Temperature regulation
oscillating between freezing to death with a few night sweats thrown in
In context ↗ - Anxiety & low mood
over past decades of struggles against chronic depression & anxiety
In context ↗ - POTS & dysautonomia
So dysautonomia it is!
In context ↗