Long COVID foot vessel ruptures, nearly normal after pycnogenol and B12

Condition: Long COVID
At worst: Mild (working or studying, with limits)
Ill before improving or writing: 4 months
Last post: Oct 2026

In their words

Condition: Long COVIDMy version of Long Covid included one of the lesser reported symptoms of spontaneous blood vessel ruptures in my feet, which was pretty freaky. In context ↗
At worst: MildI was fortunate to only have a mild version- I had vascular/circulatory issues (including spontaneous blood vessel ruptures in my feet), leg tingling, and neuroinflammation resulting in anxiety and panic attacks. In context ↗
Now: Near normalI've had some minor flareups of the lower leg stiffness but not nearly as bad as the original flare and I haven't had anymore blood vessel ruptures. In context ↗
Began after: COVIDI had a likely case of Covid in March of 2020, but I didn't qualify for testing at the time to confirm it In context ↗
Says they never had: Post-exertional malaisePEM has thankfully not been one of my long haul symptoms

Read from 251 of their posts and comments; links to the 62 this page draws on

Summary

Their long COVID was mainly vascular. After likely COVID-19 in March 2020 they developed lower-leg circulation problems and spontaneous blood-vessel ruptures in their feet; high-dose pycnogenol with krill oil improved the circulation within weeks and resolved it over months, and a later flare mostly settled after upping the supplements, though tingling remained. Methylcobalamin B12 helped the tingling, and high-dose curcumin with resveratrol helped anxiety spikes from brain inflammation.

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What they tried

What they credit

medical qigong· Helped a lot pycnogenol (French maritime pine bark extract)· Helped a lot · main · wore off curcumin (Theracurmin / Natural Factors CurcuminRich)· Helped a lot · main methylcobalamin B12 lozenges· Helped a lot ubiquinol (active CoQ10)· Helped a lot adding animal foods back into the diet· Helped gluten-free, dairy-free diet· Helped gluten-free, dairy-free diet· Helped krill oil (Jarrow)· Helped · wore off trans-resveratrol· Helped l-theanine· Helped Active Herbs Ease Tonic· Helped bioidentical progesterone drops (Progest-E)· Helped shorter, more frequent walks· Helped xylitol nasal spray (Xlear)· Helped

Also tried

colostrum supplement that contained lactoferrin· Helped a lot cold/cool baths· Helped a lot cold laser / low level laser therapy· Helped a lot lymphatic massage and essential oils· Helped a lot CDP choline· Helped a lotchiropractor (manual repositioning and cold laser)· Helped a lotvit. K2· Helped salt (Redmond Real Salt) in drinking water· Helped quercetin (EMIQ form)· Helped glutathione (Setria, liposomal, s-acetyl)· Helpedhydrogen peroxide nasal spray· Helpedlicorice extract· Helped glycine powder· Helped Paxlovid· Helped alpha GPC· Helped magnesium· Helped SAMe· Helped tyrosine· Helped acupuncture· No change iodine· Worse turkey tail mushroom· Worse astragalus· Worse He Shou Wu (polygonum multiflorum)· Not said Uncaria Tomentosa (South American cat's claw)· Not said digestive enzymes· Not said aspirin· Not said Claritin / Zyrtec· Not said Claritin / Zyrtec· Not said vitamin D· Not said vitamin A· Not said berberine· Not said black seed oil (nigella sativa)· Not said serrapeptase· Not said dandelion leaf/root tea· Not said arteminisin· Not said NAC· Not said zinc lozenges· Not said nitric oxide mix· Not said creatine· Not saidgentle bouncing on a mini trampoline· Not saidCOVID vaccination as treatment· Not said

Their words about each treatment

colostrum supplement that contained lactoferrin · Helped a lotI ended up trying a colostrum supplement that contained lactoferrin and that was what finally broke that cycle. In context ↗
medical qigong · Helped a lotthe thing that really helped the most to get over the serious fatigue ... was actually a type of energy work called medical qigong In context ↗
acupuncture · No changeafter trying 6 months of acupuncture/herbs with no difference In context ↗
iodine · Worseexperimented with iodine (it gave me heart palps and made me feel a little speedy In context ↗
He Shou Wu (polygonum multiflorum) · Not saidI've used it on and off over the years to manage/reverse thyroid-related hair loss. In context ↗
Uncaria Tomentosa (South American cat's claw) · Not saidI've used Uncaria Tomentosa (South American cat's claw) over the years for general immune support and for treating candida In context ↗
adding animal foods back into the diet · Helpedmy health improved a lot when I added meat back into my diet after not eating it for 16 years In context ↗
gluten-free, dairy-free diet · HelpedRemoving gluten and dairy made a big difference and I also take immune modulating supplements. In context ↗
vit. K2 · HelpedI really think taking vit. K2 has helped me to avoid cavities over the years. In context ↗
digestive enzymes · Not saidI took digestive enzymes to be on the safe side but I didn't have any issues. In context ↗
salt (Redmond Real Salt) in drinking water · HelpedI add salt (I like Redmond Real Salt) to all my drinking water and it makes a big difference for me. In context ↗
quercetin (EMIQ form) · HelpedI take Natural Factors EMIQ ... it helps so much In context ↗
glutathione (Setria, liposomal, s-acetyl) · HelpedI use a combo of high dose Setria glutathione and Theracurmin (a highly absorbable curcumin) for inflammation support. In context ↗
hydrogen peroxide nasal spray · HelpedI snorted hydrogen peroxide ... it usually knocks out colds for me In context ↗
pycnogenol (French maritime pine bark extract) · Helped a lotPycnogenol was the MVP in resolving my vascular/circulatory long haul symptoms. In context ↗
krill oil (Jarrow) · HelpedI also took krill oil to thin my blood. These together resolved my circulation problems. In context ↗
aspirin · Not saidbut this last time I added aspirin, too In context ↗
licorice extract · HelpedI also take licorice extract, which helps a bit with low BP (and also low cortisol). In context ↗
curcumin (Theracurmin / Natural Factors CurcuminRich) · Helped a lothigh doses of water soluble curcumin (Theracurmin form) resolved my anxiety In context ↗
trans-resveratrol · HelpedCurcumin and resveratrol work synergistically for brain inflammation. In context ↗
cold/cool baths · Helped a lotWhenever my body is feeling inflamed, I take a cold bath and it makes a huge difference In context ↗
l-theanine · HelpedTaking l-theanine and Active Herbs Ease Tonic (a traditional Chinese herbal formula for anxiety, depression, and PMS) do help a lot In context ↗
Active Herbs Ease Tonic · HelpedActive Herbs Ease Tonic (a traditional Chinese herbal formula for anxiety, depression, and PMS) do help a lot In context ↗
methylcobalamin B12 lozenges · Helped a lotThe tingling totally subsided after a couple of weeks! In context ↗
ubiquinol (active CoQ10) · Helped a lotI took 300 mg. of ubiquinol (active CoQ10) for about a week and it really did make a massive difference. In context ↗
Claritin / Zyrtec · Not saidI double dose Claritin with no issues. In context ↗
bioidentical progesterone drops (Progest-E) · Helpedwhen I added the progesterone, it made quite a difference. In context ↗
vitamin D · Not saidI ended up with elevated D at a 10k/day for a month. In context ↗
vitamin A · Not saidwe need vit. A alongside vit. D ... I develop keratosis pilaris on the back of my arms, which, for me, is a sign of A deficiency In context ↗
cold laser / low level laser therapy · Helped a lotI've had it done to treat a badly sprained knee ligament and to treat a circulatory issue in my leg ... It was extremely effective for both things. In context ↗
lymphatic massage and essential oils · Helped a lotI was able to resolve it in less than a week with lymphatic massage and essential oils used topically for lymph function In context ↗
glycine powder · HelpedMy favorite calming supplement is glycine powder. In context ↗
Paxlovid · HelpedI opted for Paxlovid as soon as I tested positive In context ↗
berberine · Not saidI started berberine (similar effects as Metformin) In context ↗
black seed oil (nigella sativa) · Not saidblack seed oil (this has specific immune modulating benefits for Hashimoto's) In context ↗
serrapeptase · Not saidI took serrapeptase on and off for inflammation but I didn't take natto. In context ↗
turkey tail mushroom · Worseturkey tail mushroom causes a spike in my anxiety levels after a few days of use In context ↗
astragalus · WorseI've made the mistake a few times of trying supplements like turkey tail mushroom or astragalus that ended up overstimulating my already overactive TH1 response In context ↗
dandelion leaf/root tea · Not saiddandelion leaf/root tea In context ↗
arteminisin · Not saidI took the remainder of a bottle of arteminisin I had laying around In context ↗
NAC · Not saidcurcimin/resveratrol (for neuroinflammation), NAC, krill oil, serrapeptase In context ↗
CDP choline · Helped a lotI took CDP choline and it helped tremendously. In context ↗
alpha GPC · HelpedI found that alpha GPC (a form of choline) was really helpful In context ↗
chiropractor (manual repositioning and cold laser) · Helped a lotI had one in 2020 and ended up needing to see a chiropractor to manually reposition my stomach, and he also treated me with cold laser. It helped so much In context ↗
nitric oxide mix · Not saidshe put me on a nitric oxide mix and had me take it and then do just a minute of exercise to boost NO In context ↗
creatine · Not saidOnce I started lifting weights, I also added creatine to help maintain muscle mass. In context ↗
magnesium · Helpedit resolved by bumping up my magnesium In context ↗
SAMe · HelpedSAMe, tyrosine, and theanine all help to boost my dopamine In context ↗
shorter, more frequent walks · Helpedshorter, more numerous walks rather than a big long walk can make such a difference in what my body tolerates! In context ↗
gentle bouncing on a mini trampoline · Not saidI've also been doing gentle health bouncing on my mini trampoline In context ↗
xylitol nasal spray (Xlear) · HelpedI really think it's probably prevented me from getting reinfected. In context ↗
COVID vaccination as treatment · Not saidI had a sore arm and a mild headache all day the next day In context ↗

Approaches: Alternative therapies · Amino acids and carnitine · Diet · Mind-body practices · Other drugs and medicines · Pacing · Sex hormones · Supplements

Their path

How ill they were on the ME/CFS severity scale, estimated from what they describe at each point, with time counted from when the illness began. Hover or tap a point. Dates are when they posted. What the levels mean.

Show as a table

When	What happened	Where they were	After
March 2020	likely COVID-19: sharp headache, mid-back ache, viral fatigue, lung inflammationI had a likely case of Covid in March of 2020, but I didn't qualify for testing at the time to confirm it In context ↗	Mild
about six weeks after onset	lower-leg circulation problems and spontaneous blood vessel ruptures in her feetMaybe about 6 weeks after my initial symptoms, I started having serious circulation issues in my lower legs. In context ↗	Mild
mid 2020	circulation symptoms resolved; total remission for about a yearI managed to resolve the circulation issue with supplements (pycnogenol and krill oil) In context ↗	Near normal	Pycnogenol and grape seed extract
May 2021	flare of circulation problems in the whole right leg, followed by tingling down the legI recently had a flareup but it only lasted about five days (but it affected my entire right leg instead of just from the knee down like last time) In context ↗	Mild
June 2021	flare mostly resolved after raising supplements; slight tingling remainedIt mostly resolved after upping those supplements again, but I'm still having just a little tingling In context ↗	Mild	Pycnogenol and grape seed extract
2021	new anxiety, felt in the body and worse at nightI wonder if my heightened anxiety is another post-Covid symptom. I had assumed it was just perimenopausal but now I wonder (or maybe it's both). In context ↗	Mild
December 2022	leg muscles that ran out of power on inclines improvedI took 300 mg. of ubiquinol (active CoQ10) for about a week and it really did make a massive difference. In context ↗	Near normal	CoQ10 / ubiquinol
October 2023	COVID reinfection followed by a cold; ill for nearly a monthI got it on Oct. 17th ... Overall, between Covid, the fatigue, and the subsequent cold, I was sick for nearly a month. In context ↗	Mild
late 2023	years of panic attacks, doom feelings and intrusive thoughts vanished on high-dose curcuminthe panic attacks and heightened anxiety I'd had for a few years that I thought was perimenpause (which I now think was LC) vanished In context ↗	Near normal
October 2026	vascular symptoms resolved; occasional minor flares and anxiety managed with supplementsI was fortunate to only have a mild version- I had vascular/circulatory issues (including spontaneous blood vessel ruptures in my feet), leg tingling, and neuroinflammation resulting in anxiety and panic attacks. In context ↗	Near normal

Adverse events

COVID vaccination as treatment“I had a sore arm and a mild headache all day the next day” In context ↗ Side effects
COVID vaccination as treatment“My second dose gave me moderate aches/fever/chills” In context ↗ Side effects
AHCC and medicinal mushrooms (reishi, shiitake, maitake)“if I take Th1 immune stimulating supplements (for example, certain medicinal mushrooms or echinacea), it can make my symptoms flare up much worse” In context ↗ Autoimmune or inflammatory flare
COVID vaccination as treatment“I did end up having a swollen lymph node in my left armpit” In context ↗ Side effects
AHCC and medicinal mushrooms (reishi, shiitake, maitake)“turkey tail mushroom causes a spike in my anxiety levels after a few days of use due to an uptick in neuroinflammation for me” In context ↗ Autoimmune or inflammatory flare
AHCC and medicinal mushrooms (reishi, shiitake, maitake)“I can't take turkey tail for more than a couple of days before it flares my autoimmunity.” In context ↗ Autoimmune or inflammatory flare
“Inulin, chicory root, and FOS bloats me up like *crazy*.” In context ↗ Gut side effects
Vitamin D and sun exposure“when I take a lot of D with no A, I develop keratosis pilaris on the back of my arms, which, for me, is a sign of A deficiency” In context ↗ Refeeding or deficiency problems
Astragalus“I have Hashimoto's and react to some immune stimulants like astragalus and turkey tail, but I tolerate cat's claw well.” In context ↗ Autoimmune or inflammatory flare
Iodine“it gave me heart palps and made me feel a little speedy, which makes me suspect it made me a little hyperthyroid at times” In context ↗ Heart rhythm problems
Cetirizine (Zyrtec)“I've never had any side effects from any second generation H1 blockers other than that Zyrtec ramps up my appetite in an annoying way.” In context ↗ Side effects

Symptoms mentioned

Anxiety & low mood Brain fog Flu-like symptoms Gut problems Hair loss Headaches & migraine Mast cell (MCAS) & allergies Muscle weakness Neuropathy & tingling POTS & dysautonomia Pain & fibromyalgia

Their words about their symptoms

Brain fogI had concentration/attention problems after my second infection last autumn In context ↗
Neuropathy & tinglingI had started to have nerve tingling down the back of my leg and even had it fall asleep while laying in bed In context ↗
Anxiety & low moodI developed an anxiety disorder, including panic attacks and sometimes intrusive thoughts during heightened anxiety. In context ↗
Mast cell (MCAS) & allergiesMy allergies also got 1000x worse that spring and now seem to last most of the year In context ↗
Headaches & migraineI woke up one morning with a sharp headache, which is so rare for me In context ↗
Gut problemsreplaced by diarrhea, which just lasted that day In context ↗
Muscle weaknesswhen I walk up a hill, it feels like my leg muscles literally just run out of power and almost stop working In context ↗
POTS & dysautonomiasome days I get lightheaded and my BP historically runs low In context ↗
Flu-like symptomsI had flu-like symptoms (fever, mild chills, moderate muscle aches, fatigue) the first evening of testing positive In context ↗
Pain & fibromyalgiamysterious shoulder/bicep pain flares that resemble polymyalgia rheumatica that I occasionally get In context ↗
Hair lossI've used it on and off over the years to manage/reverse thyroid-related hair loss In context ↗

Long COVID foot vessel ruptures, nearly normal after pycnogenol and B12

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What they tried

What they credit

Also tried

Their path

Adverse events

Symptoms mentioned

Ask Miruvor AI

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What they tried

What they credit

Also tried

Their path

Adverse events

Symptoms mentioned

Ask Miruvor AI

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