Miruvor

PDE5 inhibitors (sildenafil, tadalafil)

26 people describe trying PDE5 inhibitors (sildenafil, tadalafil) (20 with ME/CFS, 6 with long COVID).

58%
recovered fully or nearly
15 of 26
38%
improved (substantial or partial)
10 of 26
0%
relapsed
0 of 26
4%
no benefit
1 of 26

How it went

Did it last?

  • 2 of 26 said the benefit wore off.
  • 3 of 26 needed to keep doing it to stay well.

Read from what people wrote. A story that ends without a follow-up counts as lasting, so treat these as minimums.

Outcome describedAccountsShare
Full recovery1142%
Near-full415%
Substantial727%
Partial312%
Relapsed00%
No benefit14%

By how ill people were

Severity at worstHow it wentnRecovered
Moderate333%
Severe1258%
Very severe771%

4 accounts don’t say how ill the person was.

Who published these accounts

Sells a treatment or program10 accounts
50%
Recovery advocacy site8 accounts
75%
Independent (blog, forum, news)8 accounts
50%

38% of these accounts are on pages that sell this treatment or a program around it. Those pages publish their successes; compare the independent row.

All 26 accounts

  • Jordan - Long Covid Recovery Story

    Partial Long COVID ModerateIll 1.83 years cfsrecovery.com · sells Mar 2026

    Credits brain retraining. Jordan was ill 22mo with moderate long COVID and reports a partial improvement. Resigned job from fatigue; regained pet-sitting and socialising.

  • Melody's ME/CFS, Fibromyalgia and Long COVID Recovery Story

    Near-full ME/CFS SevereIll 3 years healthrising.org · sells Jun 2024

    Melody was infected early in the pandemic, hospitalised with double pneumonia, then bedbound for six months and homebound on supplemental oxygen for two and a half years despite thirteen prescription drugs and multiple specialists. She credits a combination…

  • the best treatments I've found

    Substantial ME/CFS forums.phoenixrising.me · sells Aug 2023

    Shanti1 credits this vasodilator/oxygen combination with improving brain circulation and says episodes of feeling oxygen-starved, once frequent, are now rare, describing sustained improvement "over time as underlying conditions addressed." No specific doses…

  • Michelle

    Substantial Long COVID Very severeIll 6 months longcovidcured.com Jan 2023

    Michelle saw more than ten specialists and tried extensive medical treatment: beta blockers, the migraine drug Ubrelvy, meclizine for dizziness, two rounds of prednisone, B12 shots for neuropathy, and Paxlovid taken months after her initial infection, plus…

  • I have learnt with this condition people get better from hope, kindness and love, not fear and catastrophe

    Full recovery Long COVID SevereIll 9 months recoverynorway.org Dec 2021

    Credits cognitive retraining developed with an unnamed psychology PhD candidate from Norway who had herself recovered from post-viral fatigue syndrome, after months in a self-organised online pacing support group and a referral to an NHS CFS/ME specialist…

  • Mallory's Dangerous Spinal Treatments Eventually Work

    Full recovery ME/CFS Very severeIll 9 yearsEffect faded healthrising.org Nov 2021

    Mallory had ME/CFS with several comorbid conditions and was mostly bedbound for around nine years. He pursued two experimental spine treatments: GHK-Cu peptide injections to stabilise his spine, and frequency specific microcurrent for a tethered cord, which…

  • Some Patients Are Reporting Recovery from Long COVID (Sherri)

    Substantial Long COVID SevereIll 11 months time.com Jun 2021

    Sherri Klipowicz used a plant-heavy, low-gluten, low-dairy diet, restorative yoga, magnesium and glutathione supplements, and ozone therapy, and worked with an insomnia specialist to fix her sleep. She had been sick with Long COVID since March 2020, and…

  • Oda Shares Her POTS and ME/CFS Recovery After 10 Years Using ANS REWIRE

    Full recovery ME/CFS SevereIll 10 years cfsunravelled.com · sells Apr 2021

    Oda's recovery combined daily thyroxine for diagnosed Hashimoto's hypothyroidism with the ANS REWIRE program (daily meditation and "postural rewiring" videos starting July 2017), gentle home yoga via the Yoga Studio app, one session of Thomas Hanna-method…

  • The best thing I have done is to say: no way will I accept that my daughter will just lie there and suffer indefinitely, without us being able to do anything

    Substantial ME/CFS SevereIll 2.5 years recoverynorway.org Dec 2020

    Her mother credits a phone consultation and course with Lightning Process coach Live Landmark, alongside a four-week stay, later repeated, at the Catosenteret rehabilitation centre run by Dr Bard Fossli Jensen, for her daughter's recovery from ME. Before…

  • Since my recovery, I have completed medical school and worked as a doctor – full-time

    Full recovery ME/CFS ModerateIll 9 months recoverynorway.org Jun 2020

    Thomas Overvik, a medical student, attended a three-day Lightning Process course in London in summer 2011 after about nine months of illness that began roughly eight months into medical school in autumn 2010, bringing repeated infections, headaches,…

  • My daughter was ill for eight years, lying in the dark, being fed through a tube. Today she is well

    Full recovery ME/CFS Very severeIll 8 years recoverynorway.org Jun 2020

    Her father Thomas Overvik credits the Lightning Process, taught by phone and then in a course with Live Landmark in November, for her recovery, after the family had resisted trying it for more than six years. She had been ill for about eight years with…

  • I was 13 years, and had no energy at all, but now I live my life the way I want to

    Full recovery ME/CFS Very severeIll 3 years recoverynorway.org Apr 2019

    Recovered through a structured activity-management programme run by a specialist children's CFS/ME service, pairing bursts of exertion with mandatory rest periods, plus sleep medication and a very gradual, multi-year return to schooling that began with ten…

  • Sirin Gnadeberg Shares How She Cured Her ME/CFS and POTS

    Full recovery ME/CFS SevereIll 5 years cfsunravelled.com · sells Apr 2019

    Sirin Gnadeberg added salt to her drinking water starting in April 2016, which significantly improved her POTS symptoms, then took 16 weeks of antibiotics after a Lyme specialist found elevated antibodies to Bartonella, Chlamydia and Mycoplasma (despite…

  • If I had believed all the negative things I read on the net, I would not have recovered

    Full recovery ME/CFS SevereIll 1 year recoverynorway.org Jan 2019

    Lea attended a three-day Lightning Process course run by Live Landmark after roughly a year of illness that included acupuncture, naprapathy, medical yoga and cutting out gluten and sugar, none of which had helped. Before the course she was diagnosed with…

  • For me it was about realising that the mind and body is connected, and learn that I could influence my health through cognitive tools

    Full recovery ME/CFS Very severeIll 1.08 years recoverynorway.org Jan 2019

    Recovered through a three-day Lightning Process course, learning "cognitive tools" that he says had "an immediate effect" on his physical and mental health, after care from public and private clinics and multiple doctors and hospital specialists had not…

  • Need to delete this. [Deleted]

    Partial ME/CFS ModerateIll 4 years healthrising.org Aug 2017

    Was diagnosed with ME/CFS first, then four years later diagnosed with Lyme disease and treated with a combination of pharmaceutical and herbal antibiotics under a Lyme specialist, and separately started cholestyramine with EPA/DHA fish oil after also…

  • This Is Why I Quit Exercise Therapy

    No benefit ME/CFS SevereIll 5 months buzzfeed.com Aug 2017

    Graded exercise therapy, prescribed by an NHS specialist, started with five minutes of walking a day and increased weekly, reaching six minutes in week two and continuing upward. She had been unwell for roughly five months, with flu-like exhaustion, joint…

  • Fearing Death Was at Hand, Fred Finds an Answer

    Substantial ME/CFS SevereIll 15 years healthrising.org · sells Aug 2016

    Fred, a university professor, became severely ill with an acute flu-like onset in 1991 and was homebound by 2006. Valcyte under Dr Lerner's protocol brought him to about 75% functioning within six months, letting him socialise, travel and do home…

  • Mestinon, Chronic Fatigue, Vagus Nerve Stimulation and Exercise

    Substantial ME/CFS Very severeIll 28 years healthrising.org Jun 2016

    After 28 years of never being able to exercise despite seeing top ME/CFS specialists worldwide, and a recent low point involving surgeries, ER visits and a drug reaction, this patient started 180mg/day Mestinon and within weeks felt an urge to run for the…

  • Dan Moricoli - On the Path - and Recovering From ME/CFS

    Near-full ME/CFS Very severeIll 8 years healthrising.org Mar 2015

    Started a heart-rate-monitored graded exercise and pacing program in 2008, beginning with two 5-minute walks every other day with 10-20 minute rest periods, alongside a sleep specialist referral that improved sleep from 2-4 hours to 5 hours nightly, a strict…

  • Has anyone achieved remission or recovery from treatment by any doctor?

    Near-full ME/CFS forums.phoenixrising.me Mar 2015

    SOC's daughter took two years of combined antivirals, Valcyte (valganciclovir) and Valtrex (valacyclovir), prescribed by an ME/CFS specialist. Beforehand she had been declining, sitting around activity level 4-5; on the antivirals she rose to about level 8-9…

  • Has anyone achieved remission or recovery from treatment by any doctor?

    Full recovery ME/CFS forums.phoenixrising.me Mar 2015

    SOC does not name specific drugs or doses, but says antivirals from an ME/CFS specialist lifted them from a severely disabled level of about 1 on a self-rated activity scale to about 3-4 over several years, while a later specialist's broader range of…

  • My recovery story

    Full recovery ME/CFS SevereIll 5 yearsEffect faded forums.phoenixrising.me · sells Dec 2010

    Ian says a specialist identified necrotic "cavitation" lesions in his jawbone and that surgical removal eliminated his years-long feeling of being "chronically poisoned," resolving most CFS symptoms. The first surgery's benefit faded months later when the…

  • AcuPips - Original Ear Seed Specialists

    Partial Long COVID acupips.com · sells

    AcuPips ear seeds (self-administered acupressure), duration of use and placement not specified. She had post-COVID headaches, with no other long-COVID symptoms or overall illness duration and severity stated. She reports relief within about two weeks of use.…

  • Primal Trust testimonials: Carrie Martin

    Substantial ME/CFS SevereIll 7 years primaltrust.org · sells

    Credits brain retraining. Carrie was ill 7y with severe ME/CFS and reports a substantial improvement. CFS from Lyme; returning to work and socialising.

  • My Long Covid Solution: I Feel Like a Different Person

    Near-full Long COVID SevereIll 7 months lightningprocess.com · sells

    Credits the Lightning Process. Charlotte was ill 7mo with severe long COVID and is described as almost fully recovered. Driving, cooking, socialising within 7 weeks post-course.